Posts Tagged ‘radiation’

BRCA1 or BRCA2 Genes, Aggressive cancer Of The Prostate, And Treatment

 Mutant Gene Linked To Aggressive Cancer Of The Prostate

US researchers have found that men with prostrate cancer have an increased risk of aggressive tumor if they are carriers of a gene mutation which is normally linked to breast cancer in women.

This finding could have major implications in treatment options for prostrate cancer

If a patient carries the mutated gene, he may want to opt against watchful waiting of prostrate cancer, where it is just monitored and not treated.

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Surgery or radiation treatment may be the best option here.

It is difficult to distinguish between aggressive tumors and the ones that may stay without spreading or enlarging. The researchers examined 979 men with prostrate cancer and 1251 men without the cancer. They looked at whether the men carried the mutations of the BRCA1 or BRCA2 genes. These are the genes that cause an increased risk of breast and ovarian cancer in women.

Only Ashkenazi Jews were included in the study because they are five times more likely to carry the mutation in the genes than the general population. The study found that the mutations did not increase the risk of a man getting prostrate cancer, but those who already had the cancer stood a higher risk of having a more aggressive tumor.

Prostate cancer is the most common cancer, after skin cancer, in America. It affects one in six
men

Statistically, more than 192000 men are likely to be diagnosed with prostate cancer in 2009. More than 27000 men also die from it. Every 2.7 minutes one new case occurs and a patient dies from the disease every 19 minutes.

More than 2 million Americans are estimated to have this disease currently. Old age, family history of prostrate cancer and African American race are factors that increase the likelihood of this disease.

As men grow older, the risk of developing prostrate cancer increases exponentially

1 in 10,000 under the age of 40 will be diagnosed with prostrate cancer. From the ages of 40 to 59, this rate shoots up to 1 in 39. From 60 to 69 years of age, it is 1 in 14. More than 65% of prostate cancer diagnoses are made in men above the age of 65.

African American men have 56% more likelihood to develop prostate cancer than Caucasian men. They are also 2.5 times as likely to die from the disease.

If the father, brother or son has a history of prostrate cancer, the man is twice as likely to develop the disease. If two or more relatives have prostrate cancer history, the likelihood increases to four times.

Now the study conducted on gene mutation and prostrate cancer, estimates that participants with aggressive tumors had 3.2 times more likelihood of carrying the BRCA2 gene mutation than the men in control group.

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Here are some more informative articles about prostate cancer and genetics…

Control the Epstein Barr, Hepatitis, and Herpes Viruses With Gene 

The release mentions Dr. Illa R Singh from the University of Utah who said about his recently published research that “for the first time we have analyzed prostate cancer and normal prostate tissue and found cancers are much more likely to … According to Dr. Polansky, chronic viruses are genetic parasites, which “starve” human genes and cause them to behave as if they have been mutated. Now, we all know that mutated genes cause cause cancer

Virus Infection May Cause Some Cases of ‘Fatigue Syndrome 

The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific endoribonuclease involved in the antiviral actions of IFNs. … A mutation can be good or bad or indifferent. The results shift over time. Genes for one situation can become very bad in another situation. Exposure to many different genetic agents both alien and domestic can cause swift and huge changes inside the organism even leading to death. 

Cancer Gene BRCA 2  The Word Is Hope

So if a test shows the mutated gene is present there are certain steps you can take. Ob fef viously regular screening is essential. Remember that the best cancer is no cancer but if it does occur, early detection gives you the greatest chances

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Treatments for Prostate Cancer

Aside from skin cancer, prostate cancer is the most common form of cancer found in men. Statistics show that 1 in every 6 men will be diagnosed with prostate cancer at some point in their life. As a result, scientists are constantly researching new treatments for prostate cancer.

The prostate, an organ found only in men, is an important part of the uro-genital system. It is located below the bladder and surrounds the urethra, which connects to the bladder and allows for the evacuation of urine. The prostate, like any other organ, is susceptible to carcinoma and the need for new treatment is overwhelming. While many researchers focus on prevention, there are others who do focus on treatment. While prevention is important, for those already diagnosed with prostate cancer new treatment is necessary.

One new treatment for prostate cancer is HIFU (High Intensity Focused Ultrasound). This treatment destroys the cancerous tissue by using sound waves. Sound waves are aimed directly at the cancer and focused until they heat the tissue to approximately 90 degrees Celcius and literally cook the tumor away. The procedure takes 1 – 4 hours to complete and it is done under spinal anesthesia. As with many new treatments, High Intensity Focused Ultrasound is, for now, only available outside of the United States. It does however, show great promise. Internationally, over 6000 men have had this procedure performed successfully.

In conclusion, prevention is the key for those with a significant family history but who have not yet been diagnosed. For those who are currently living with the diagnosis of prostate cancer new treatment brings a ray of hope. There is constant research being performed in the area of prostate cancer and High Intensity Focused Ultrasound is the most recent breakthrough in the treatment of this terrible disease.

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Prostate Cancer Treatment, Info And Options

One common form of treatment today for localized prostate cancer is radiation therapy which uses high energy x-rays to kill cancer cells. These x-rays can either be delivered using an external radiation beam or by implanting radiation ’seeds’ into the prostate gland.

Treatment options for advanced prostate cancer

External beam radiation therapy treatments are normally given on a daily basis 5 days a week (Monday to Friday) for anything up to about 6 or 7 weeks and each treatment, which is painless, lasts for just a few minutes.

Such treatments are also commonly given to patients whose cancer is no longer localized to the prostate gland but has spread into the pelvis and can also be used to relieve pain and reduce tumors in cases of advanced prostate cancer.

In cases where tumors are large it is also common to give hormone treatment alongside radiation therapy in order to block the action of the male hormones which feed the growth of prostate cancer tumors. Such hormonal treatments are often continued for many months, or even years.

radiation therapy

External beam radiation targets not only the prostate gland but also the seminal vesicles, to which prostate cancer can readily spread.

In previous forms of this treatment it was also common to irradiate the pelvic lymph nodes but today this is only done in a minority of cases where evidence suggests that this is necessary.

There are generally few immediate side-effects to external beam radiation other than fatigue and possibly diarrhea when radiation is applied to the rectum, but both of these soon pass once treatment is completed.

Longer-term affects include impotence which affects about 40% to 50% of patients. This figure is however declining with the introduction of computer technology which now allows treatment to be tailored precisely to the anatomy of the patient with far more precise targeting than has previously been possible.

Internal radiation Therapy

Turning to internal radiation therapy, this is a procedure in which dozens of tiny seeds are implanted directly into the prostate gland to deliver a high dose of radiation directly into the affected tissue.

Ultrasound is used to guide very thin needles from the perineum into the prostate gland to deposit the tiny seeds of palladium and iodine in a pattern which has previously been mapped using a very sophisticated computer program. The procedure, which usually takes about an hour, is carried out under local anesthetic and the patient is normally allowed home the same day.

One alternative approach is to use more powerful temporary seed implants which are introduced over several days and possibly to combine this with low dose external radiation therapy. This procedure does however require hospitalization.
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Internal radiation therapy carries few side-effects and normally leads to impotence in less that 15% of patients under the age of 70. It is not however suitable for everybody, especially men with large tumors or those who have undergone a transurethral resection of the prostate for benign prostatic hyperplasia.

For non-surgical, non-invasive options for prostate cancer there are a whole range of alternative natural therapies available and many testimonials which tout their effectiveness so do your research before opting immediately for surgery and more drastic measures

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Here are a few more Related Posts to browse…

Treatments after prostate surgery reported
Although primary prostate surgery or radiotherapy is successful in many cases of prostate cancer, some patients will suffer a recurrence of the disease, which is most often first detected by a measurable PSA blood test.

Baby Powder, Soft Pillows and Other Cancer Wisdom
For nearly a year, Times editor Dana Jennings has been coping with an aggressive form of prostate cancer. Recently, one of his good friends was diagnosed with the disease and is soon scheduled for surgery. Dana Jennings.

Correlation Between Prostate Cancer And Smoking
Smoking has a detrimental effect on the body in many ways. However, not many people realize all the harm that it can do. New evidence suggests that it may even cause advance stages of cancer of prostate in men.

Multiple Myeloma News: Prostate treatment 95% effective, study shows
Other forms of treatment for prostate cancer are surgery to remove the cancer mass, or external beam radiation to destroy it. Keyes said the agency has developed a fourth method called active surveillance.

I need to know about symptoms after Prostate Cancer surgery
My husband had complete prostate removal surgery 5-05 and has the usual problems associated with that but has another side effect his Dr’s. wont even.

Find more information on a wide range of prostate problems and also provides advice on many topics including the therapeutic use of prostate milking for BPH sufferers.

Article By Donald Saunders

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