Prostate Cancer Care

Posts Tagged ‘of’

 Mutant Gene Linked To Aggressive Cancer Of The Prostate

US researchers have found that men with prostrate cancer have an increased risk of aggressive tumor if they are carriers of a gene mutation which is normally linked to breast cancer in women.

This finding could have major implications in treatment options for prostrate cancer

If a patient carries the mutated gene, he may want to opt against watchful waiting of prostrate cancer, where it is just monitored and not treated.

> Beat Cancer Naturally. Learn More here

Surgery or radiation treatment may be the best option here.

It is difficult to distinguish between aggressive tumors and the ones that may stay without spreading or enlarging. The researchers examined 979 men with prostrate cancer and 1251 men without the cancer. They looked at whether the men carried the mutations of the BRCA1 or BRCA2 genes. These are the genes that cause an increased risk of breast and ovarian cancer in women.

Only Ashkenazi Jews were included in the study because they are five times more likely to carry the mutation in the genes than the general population. The study found that the mutations did not increase the risk of a man getting prostrate cancer, but those who already had the cancer stood a higher risk of having a more aggressive tumor.

Prostate cancer is the most common cancer, after skin cancer, in America. It affects one in six men

Statistically, more than 192000 men are likely to be diagnosed with prostate cancer in 2009. More than 27000 men also die from it. Every 2.7 minutes one new case occurs and a patient dies from the disease every 19 minutes.

More than 2 million Americans are estimated to have this disease currently. Old age, family history of prostrate cancer and African American race are factors that increase the likelihood of this disease.

As men grow older, the risk of developing prostrate cancer increases exponentially

1 in 10,000 under the age of 40 will be diagnosed with prostrate cancer. From the ages of 40 to 59, this rate shoots up to 1 in 39. From 60 to 69 years of age, it is 1 in 14. More than 65% of prostate cancer diagnoses are made in men above the age of 65.

African American men have 56% more likelihood to develop prostate cancer than Caucasian men. They are also 2.5 times as likely to die from the disease.

If the father, brother or son has a history of prostrate cancer, the man is twice as likely to develop the disease. If two or more relatives have prostrate cancer history, the likelihood increases to four times.

Now the study conducted on gene mutation and prostrate cancer, estimates that participants with aggressive tumors had 3.2 times more likelihood of carrying the BRCA2 gene mutation than the men in control group.

DID YOU KNOW …

… that there’s a simple formula that has been *scientifically proven* to prevent and CURE virtually all diseases? 

Find out why this one-minute therapy is being suppressed in the U.S. while more than 15,000 European doctors have been using it to heal millions of patients –

and how you can use it, too

Click Here

Author Alex White is a free lance writer and a health & fitness expert who has been associated with several health care providers across various specialties. Through his articles, Alex White wishes to inform and educate public about Prostrate Cancer. which will benefit those who are looking for resourceful information regarding health.

Article Source: ArticleSnatch Free Article Directory

Here are some more informative articles about prostate cancer and genetics…

Control the Epstein Barr, Hepatitis, and Herpes Viruses With Gene 

The release mentions Dr. Illa R Singh from the University of Utah who said about his recently published research that “for the first time we have analyzed prostate cancer and normal prostate tissue and found cancers are much more likely to … According to Dr. Polansky, chronic viruses are genetic parasites, which “starve” human genes and cause them to behave as if they have been mutated. Now, we all know that mutated genes cause cause cancer

Virus Infection May Cause Some Cases of ‘Fatigue Syndrome 

The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific endoribonuclease involved in the antiviral actions of IFNs. … A mutation can be good or bad or indifferent. The results shift over time. Genes for one situation can become very bad in another situation. Exposure to many different genetic agents both alien and domestic can cause swift and huge changes inside the organism even leading to death. 

Cancer Gene BRCA 2  The Word Is Hope

So if a test shows the mutated gene is present there are certain steps you can take. Ob fef viously regular screening is essential. Remember that the best cancer is no cancer but if it does occur, early detection gives you the greatest chances

> Learn More About The One Minute Therapy here

 Mail this post

Technorati Tags: aggressive, cancer, of, prostate, prostrate, radiation, surgery, treatment, tumor, waiting, watchful

The prostate is a glandular organ present in males. It surrounds the neck of the bladder & the first side of the urethra plus it contributes to the emission of seminal fluid.

The gland is tapering in form, 3 cm straight down diameter as well as 4 cm in sloping diameter. It has  five lobes: fore, posterior, two lateral as well as a median lobe. Seeing as it is at the initial part of the urethra passage, any lesion in the prostate will raise blockage issues in passing urine.

Diseases of the prostate gland:

• Prostatitis:

This is the inflamation of the prostate gland due to bacterial infection.

• Gentle bulge of the prostate:-

This is a non cancerous tumour of the prostate seen after the age of 50.

• Sarcoma of the prostate 

A  more serious condition which can result ultimately in death

Cancer of the prostate

Cancer of the prostate is asscociated with the male gender hormones(androgens). If the levels of this male sexual  hormone increases the growth rate of malignancy can also increase.It is noted that as soon as the removel of testes takses place there is marked reduction in the appearance of tumors.

Location of tumour

Prostate malignancy is seen predominantly in the following lobe. Non cancerous amplification is seen in supplementary lobes.

Changes in the gland in malignant cells:

The gland goes hard and bumpy along with loss of natural lobulation. Histologically prostate melanoma is an adeno carcinoma (malignancy of the epithelial cells in the gland)

Development :

The advance rate can be very fast in prostate cancer. The tumour presses the urethra in addition to produce problems in urination.

Spread of tumour:

Metastasis in malignant cells of the prostate

• Local spread

Starting with the fore lobe the malignancy cells spread to the side lobes along with determining vesicles.Tumor cells also spread to the collar along with pedestal of the urinary bladder.

• Lymphatic spread

From end to end the lymph vessel sarcoma cells reach the inner and external iliac cluster of lymph nodes. Starting nearby cells go to retroperitonial (Behind the peritonium) as well as mediastinal lymph nodes (in the chest)

• Spread from first to last the blood

Spread of sarcoma cells takes place through the periprostatic venous plexus to the vertebral veins while coughing and sneezing in addition to the vertebral bodies of the lumbar spine.

Signs and symptoms of prostate melanoma

Signs and symptoms depend on the stage of the malignant cells.

The following symptoms are listed

• No symptoms:

Tumour is miniature and only in the subsequent lobe. This is diagnosed accidentally.

• Urination:

Now the tumour is inflated as the urethra is slightly packed in. In a minute there will be a repeated urge for urination through difficult urination.

• The tumour multiplies to all in the vicinity areas as well as the neck of bladder in addition to the urethra and at this stage there will be painful urination and bleeding.

• Retention of urine:

When the urethra is utterly condensed there will be withholding of urine.This may show up as hydronephrosis, renal collapse ect. In this statethe sufferer may get convulsions due to renal failure along with finally coma.

Signs of metastasis:

a) Lumbo sacral – extending of tumor cells to lumbar along with sacral vertebrae.

b) Break of spinal column due to cancerous intensification in the spine.

c) Puffiness, pain as well as fluid collection in the abdomen due to laceration in the stomach.

d) Respiratory complaints due to tumor of mediastinal lymphnodes and lungs.

e) Common limitation due to spread of melanoma

f) Anaemia

Clinical examination :

Includes rectal exam to feel the prostate gland, palpation of tummy to feel the inflammation in kidneys and any tumours. The patient is examined beginning head to foot to search for any lesions.

Investigations

1) Whole blood investigations: RBC,WBC, Platelets, ESR, bleeding time, clotting time etc.

2) Urine analysis: Microscopic examination to detect pus cells,occult blood,casts,Crystals ect.

3) Renal function tests: Blood urea point, serum creatinine level, electrolyte level etc.

4) Serum acid phosphatase: Augmented in sarcoma of prostate.

5) x-ray of the spinal column: To notice any tumour or break.

6) Ultra sonography: Gives idea about prostate, bladder, kidney etc.

7) C T scan: More detailed information about organs in addition to tumour.

MRI of the spine: Gives complete information about spine ,disc and nearby soft tissues.

9) Lymphangiography: Gives idea about lymphatic spread of cancer.

10) Biopsy to back up suspected cancer diagnosis: Biopsy is taken plus histopathological examination of cells beneath the microscope.This will reveal the presence of sarcoma cells.

Treatment:

1) If there is retention of urine, catheterisation is needed.
2) Dialysis, if kidney malfunction.
3) If there is coma, monitoring of all crucial functions together with parentral nutrition along with electrolyte supply.
4) Specific treatment is prostatectomy (removal of prostate)

Partial prostatectomy:

At this juncture only the affected lobe is removed.

Far-reaching prostatectomy :

Total subtraction of prostate along with nearby lymphnodes.

5, Hormone therapy : Stilbestrol is given to moderate tumour escalation.Since this treatment increases the possibility for cardiovascular disease phosphorylated diethyle stilbesterol is used at the moment.

6) Chemotherapy: Drugs like cyclophosphamide, cisoplatim etc are specified.

7) Radiotherapy is also prepared for several cases.

Homoeopathy: Homoeopathic drugs akin to carcinocin, conium, sabal, crotalus, thuja, iodum, selinium, staphysagria, sulphur etc can be given according to symptoms. Constitutional homoeopathic medicine can offer  relief.

9) Yoga plus reflection and meditation is also helpful.

 Mail this post

Technorati Tags: cancer, diseases, gland, inflammation, investigations, melanoma, metastasis, of, problem, problems, prostate, prostatectomy, prostatitis, sarcoma, signs, spread, symptoms, treatment, urinary, urination